Intranasal Opioid Administration in Rhesus Monkeys: PET Imaging and Antinociception
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چکیده
منابع مشابه
Interactions between μ-opioid receptor agonists and cannabinoid receptor agonists in rhesus monkeys: antinociception, drug discrimination, and drug self-administration.
Cannabinoid receptor agonists enhance the antinociceptive effects of μ-opioid receptor agonists, which suggests that combinations of these drugs might enhance therapeutic effectiveness (e.g., analgesia). However, it is not clear whether combinations of these drugs also enhance abuse or dependence liability. This experiment examined whether combinations of cannabinoids and opioids that enhance a...
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*Correspondence: Lisa A. Parr, Department of Psychiatry and Behavioral Science, Center for Translational Social Neuroscience and Yerkes National Primate Research Center, Emory University, 954 Gatewood Rd., Atlanta, GA 30329, USA e-mail: [email protected] There are currently no drugs approved for the treatment of social deficits associated with autism spectrum disorders (ASD). One hypothesis for t...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2016
ISSN: 0022-3565,1521-0103
DOI: 10.1124/jpet.116.235192